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Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay

INTRODUCTION: Immunological protection against human immunodeficiency virus-1 (HIV-1) infection is likely to require both humoral and cell-mediated immune responses, the latter involving cytotoxic CD8 T-cells. Characterisation of CD8 T-cell mediated direct anti-viral activity would provide understan...

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Detalles Bibliográficos
Autores principales: Fernandez, Natalia, Hayes, Peter, Makinde, Julia, Hare, Jonathan, King, Deborah, Xu, Rui, Rehawi, Ola, Mezzell, Allison T., Kato, Laban, Mugaba, Susan, Serwanga, Jennifer, Chemweno, James, Nduati, Eunice, Price, Matt A., Osier, Faith, Ochsenbauer, Christina, Yue, Ling, Hunter, Eric, Gilmour, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751811/
https://www.ncbi.nlm.nih.gov/pubmed/36532063
http://dx.doi.org/10.3389/fimmu.2022.1029029