140. Enterococcus faecalis CL Synthases Have Redundant Roles and Play A Major Role in Phospholipid Redistribution Associated with Daptomycin Resistance

BACKGROUND: Daptomycin (DAP) is a lipopeptide antibiotic targeting membrane anionic phospholipids (APLs) at the division septum. DAP resistance (DAP-R) has been associated with activation of the LiaFSR system resulting in redistribution of APL microdomains (likely containing cardiolipin, CL) away fr...

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Detalles Bibliográficos
Autores principales: Nguyen, April, Polamraju, Vinathi, Zhang, Rutan, Panesso, Diana, Khan, Ayesha, Mileykovskaya, Eugenia, Cecilia Tran, Truc, Xu, Libin, Vitrac, Heidi, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751826/
http://dx.doi.org/10.1093/ofid/ofac492.218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751826/
http://dx.doi.org/10.1093/ofid/ofac492.218

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