1650. Efficacy of β-Lactam Therapy against Infections Caused by Metallo-β-lactamase (MBL)-Producing Enterobacterales: Bridging the Susceptibility Testing Gap

BACKGROUND: In vitro-in vivo discordance in the activity of β-lactams against MBL-producing Enterobacterales has been described. This discordance is likely attributed to the supra-physiologic zinc level in the in vitro testing media, which facilitates the bicyclic β-lactam ring hydrolysis. In this s...

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Detalles Bibliográficos
Autores principales: Abdelraouf, Kamilia, Gill, Christian M, Gethers, Matthew, Tiseo, Giusy, Falcone, Marco, Menichetti, Francesco, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751858/
http://dx.doi.org/10.1093/ofid/ofac492.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751858/
http://dx.doi.org/10.1093/ofid/ofac492.116

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