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D1018 with higher stability and excellent lipopolysaccharide binding affinity has potent anti-bacterial and anti-inflammatory activity

Escherichia coli (E. coli) infection and LPS-induced inflammation are still of severe threat to human health. With the increasing problem of antibiotic resistance, there is a desperate need to develop new approaches to solve the problem. Antimicrobial peptide (AMP) IDR-1018 exhibited potential antim...

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Detalles Bibliográficos
Autores principales: Wu, Runzhe, Dong, Xunxi, Wang, Qiang, Zhang, Zirui, Wang, Jianhua, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751974/
https://www.ncbi.nlm.nih.gov/pubmed/36532445
http://dx.doi.org/10.3389/fmicb.2022.1010017