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A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer

A widely used procedure for selecting significant miRNA-mRNA or isomiR-mRNA pairs out of predicted interactions involves calculating the correlation between expression levels of miRNAs/isomiRs and mRNAs in a series of samples. In this manuscript, we aimed to assess the validity of this procedure by...

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Detalles Bibliográficos
Autores principales: Nersisyan, Stepan, Zhiyanov, Anton, Engibaryan, Narek, Maltseva, Diana, Tonevitsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751988/
https://www.ncbi.nlm.nih.gov/pubmed/36531236
http://dx.doi.org/10.3389/fgene.2022.1070528