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1543. Validation of a Nitrocefin-based Rapid Test for the Detection of the Cefazolin Inoculum Effect in Pediatric Patients with Methicillin-Susceptible Staphylococcus aureus Acute Osteomyelitis

BACKGROUND: The cefazolin (Cz) inoculum effect (CzIE) defined as a Cz MIC ≥ 16 µg/mL at high inoculum (10(7) CFU/mL) in MSSA isolates has been associated with poor outcomes in adult patients with bacteremia. Recently, it was associated with higher rates of progression to chronic osteomyelitis in ped...

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Detalles Bibliográficos
Autores principales: Gomez Villegas, Sara I, Rincon, Sandra, Carvajal, Lina, Sommer, Lauren M, Botero, Diana Panesso, Reyes, Maria, Rios, Rafael, Dinh, An, Diaz, Lorena, Kaplan, Sheldon L, Reyes, Jinnethe, Flores, Anthony R, McNeil, Jonathon C, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752012/
http://dx.doi.org/10.1093/ofid/ofac492.098