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2350. LiaF is required for LiaX mediated protection against Daptomycin and LL-37 in Enterococcus faecalis OG1RF

BACKGROUND: Daptomycin (DAP) resistance in enterococci is regulated by the LiaFSR three-component regulatory system. Mutations in liaF have been linked to activation of this system, with increased expression of the protein LiaX, and resistance to DAP in clinical isolates. LiaX functions by recognizi...

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Detalles Bibliográficos
Autores principales: Botero, Diana Panesso, Singh, Kavindra, Gomez-Villegas, Sara-Isabel, Khan, Ayesha, Supande, Adeline, Nguyen, April, Rincon, Sandra, Hood, Kara S, Dinh, An, Deyanov, Alexander, Miller, William R, Shamoo, Yousif, Tran, Cecilia, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752123/
http://dx.doi.org/10.1093/ofid/ofac492.157