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2350. LiaF is required for LiaX mediated protection against Daptomycin and LL-37 in Enterococcus faecalis OG1RF
BACKGROUND: Daptomycin (DAP) resistance in enterococci is regulated by the LiaFSR three-component regulatory system. Mutations in liaF have been linked to activation of this system, with increased expression of the protein LiaX, and resistance to DAP in clinical isolates. LiaX functions by recognizi...
Autores principales: | Botero, Diana Panesso, Singh, Kavindra, Gomez-Villegas, Sara-Isabel, Khan, Ayesha, Supande, Adeline, Nguyen, April, Rincon, Sandra, Hood, Kara S, Dinh, An, Deyanov, Alexander, Miller, William R, Shamoo, Yousif, Tran, Cecilia, Arias, Cesar A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752123/ http://dx.doi.org/10.1093/ofid/ofac492.157 |
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