609. In vivo efficacy of human simulated exposures of cefiderocol (FDC) in combination with ceftazidime/avibactam (CZA) or meropenem (MEM) using in a 72 hour murine thigh infection model

BACKGROUND: Acinetobacter baumannii continues to challenge clinicians as multi-drug resistance limits therapeutic options. CFDC possesses potent in vitro and in vivo activity however combination therapy has been recommended for A. baumannii due to its propensity for multiple resistance mechanisms. T...

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Detalles Bibliográficos
Autores principales: Gill, Christian M, Santini, Debora, Takemura, Miki, Longshaw, Christopher M, Yamano, Yoshinori, Echols, Roger, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752224/
http://dx.doi.org/10.1093/ofid/ofac492.661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752224/
http://dx.doi.org/10.1093/ofid/ofac492.661

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