499. Immunotherapy with Pattern Recognition Receptor Agonists Improves Morbidity and Mortality in a Corticosteroid-Immunosuppressed Murine Model of Influenza-Associated Pulmonary Aspergillosis

BACKGROUND: Corticosteroids are known to increase the incidence and worsen the outcomes of influenza-associated pulmonary aspergillosis (IAPA) in patients with severe influenza pneumonia. Adjunct immunomodulatory strategies might improve the treatment of this emerging entity, but in-vivo data in val...

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Detalles Bibliográficos
Autores principales: Wurster, Sebastian, García, Jezreel Pantaleón, Albert, Nathaniel D, Evans, Scott, Kontoyiannis, Dimiitrios P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752376/
http://dx.doi.org/10.1093/ofid/ofac492.556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752376/
http://dx.doi.org/10.1093/ofid/ofac492.556

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