233. Safety of Ceftazidime-Avibactam (CZA) in Combination with Aztreonam (ATM) in a Phase I, Open-Label Study in Healthy Adult Subjects (COMBINE)

BACKGROUND: The combination of CZA-ATM is frequently used to treat patients with metallo-β-lactamase (MBL)-producing Enterobacterales (EB) infections, but its safety has not been established in controlled trials. This phase 1 study evaluated the safety of the optimal CZA-ATM regimens identified in t...

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Detalles Bibliográficos
Autores principales: Lodise, Thomas, Nicholas O’Donnell, J, Raja, Shruti, Balevic, Stephen, Guptill, Jeffrey, Schwager, Nyssa, Zaharoff, Smitha, Fowler, Vance G, Ghazaryan, Varduhi, Beresnev, Tatiana, wall, Alison, Wiegand, Katherine, Chambers, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752385/
http://dx.doi.org/10.1093/ofid/ofac492.311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752385/
http://dx.doi.org/10.1093/ofid/ofac492.311

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