594. An Open-Label Study in Healthy Volunteers to Determine the Absolute Bioavailability of, the Effect of Food and Dosing by Nasogastric Tube upon the Pharmacokinetics of a Single Oral Dose of Olorofim (OLO)

BACKGROUND: OLO is a novel antifungal active vs. Aspergillus (including azole-resistant strains), resistant moulds (e.g., Lomentospora prolificans), and dimorphic moulds. Information on absolute bioavailability and effect of food upon the pharmacokinetics (PK) of OLO when administered as a 30 mg tab...

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Detalles Bibliográficos
Autores principales: Cornelissen, Karen, Newell, Paul A, Rex, John H, Galbraith, Hal, Israel, Samuel, Bush, James, ChB, M B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752389/
http://dx.doi.org/10.1093/ofid/ofac492.646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752389/
http://dx.doi.org/10.1093/ofid/ofac492.646

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