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Distinctive phenotype for HLA-E- versus HLA-A2-restricted memory CD8 αβT cells in the course of HCMV infection discloses features shared with NKG2C(+)CD57(+)NK and δ2(-)γδT cell subsets

The human cytomegalovirus (HCMV) triggers both innate and adaptive immune responses, including protective CD8(+) αβT cells (CD8T) that contributes to the control of the infection. In addition to CD8T restricted by classical HLA class Ia molecules, HCMV also triggers CD8T recognizing peptides from th...

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Detalles Bibliográficos
Autores principales: Rousselière, Amélie, Gérard, Nathalie, Delbos, Laurence, Guérif, Pierrick, Giral, Magali, Bressollette-Bodin, Céline, Charreau, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752567/
https://www.ncbi.nlm.nih.gov/pubmed/36532017
http://dx.doi.org/10.3389/fimmu.2022.1063690