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2138. Evaluating the Safety and Immunogenicity of the rZIKV/D4Δ30-713 Live Attenuated Chimeric Zika Candidate Vaccine in Healthy Flavivirus-Naïve Adults

BACKGROUND: Zika virus (ZIKV) is a flavivirus associated with a serious congenital Zika syndrome, with a recent epidemic originating in Brazil in 2015. Novel ZIKV vaccine candidates are in development. We report results of a phase I study of the first live attenuated ZIKV vaccine for use in humans....

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Detalles Bibliográficos
Autores principales: Zhong, Diana, Kirkpatrick, Beth, Pierce, Kristen, Patel, Urvi, Blunt, Madeleine R, Durbin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752575/
http://dx.doi.org/10.1093/ofid/ofac492.1758