1716. In Vitro Drug-Drug Interaction Evaluation of Epetraborole, a Novel Bacterial Leucyl-tRNA Synthetase Inhibitor

BACKGROUND: Epetraborole (EBO) is a boron-containing oral inhibitor of bacterial leucyl-tRNA synthetase, an essential enzyme in protein synthesis; EBO demonstrates potent activity against nontuberculous mycobacteria. EBO is being developed for the treatment of Mycobacterium avium complex lung diseas...

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Detalles Bibliográficos
Autores principales: Shafiee, Afshin, Wong, Bradley K, Chanda, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752660/
http://dx.doi.org/10.1093/ofid/ofac492.1346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752660/
http://dx.doi.org/10.1093/ofid/ofac492.1346

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