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2072. Of Mice and Men: HIV-induced CD38 expression on CD8+ T lymphocytes contributes to mitochondrial dysfunction and chronic inflammation despite antiretroviral therapy
BACKGROUND: Antiretroviral treatment (ART) has increased the life expectancy of people with HIV (PWH), however, comorbidities are higher in PWH than HIV-negative individuals. This is partly due to accelerated cellular aging, a consequence of CD38 expression, mitochondrial dysfunction, and inflammati...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752695/ http://dx.doi.org/10.1093/ofid/ofac492.1694 |