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1813. A Population-Based Multi-Year Assessment of the Incidence of High Inoculum Cefazolin (CZ) Resistance Amongst Methicillin-Susceptible Staphylococcus aureus (MSSA) Causing Bloodstream Infections (BSIs) over time in Calgary, Canada

BACKGROUND: Cefazolin (CZ) is a 1(st)-line therapy for methicillin-susceptible Staphylococcus aureus (MSSA) infections due to its tolerability, lower toxicity, and convenient dosing. However, some strains exhibit reduced susceptibility to CZ when present in high inoculum. Treatment failure and worse...

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Detalles Bibliográficos
Autores principales: Du, Kristine, Waddell, Barbara Jean M, Ligier, Chloe, Svishchuk, Julianna, Kipp, Alexander, Lam, John, Robinson, Stephen, Somayaji, Ranjani, Conly, John M, Gregson, Daniel, Parkins, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752948/
http://dx.doi.org/10.1093/ofid/ofac492.1443