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1154. Safety, Tolerability, and Viral Pharmacodynamics of the IgG Monoclonal Antibody Sotrovimab Administered via Intramuscular Injection for the Treatment of Early Mild-to-Moderate COVID-19

BACKGROUND: There is a continued need for therapeutics for the treatment of COVID-19, including intramuscular (IM) agents, which will enable broader use across a variety of healthcare delivery settings. METHODS: COMET-PEAK (NCT04779879) is a 3-part study evaluating the safety, tolerability, pharmaco...

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Detalles Bibliográficos
Autores principales: Gupta, Anil K, Perez-Rodríguez, Maria Teresa, Gonzalez-Rojas, Yaneicy, Ramgopal, Moti, Free, Almena, Han, Jennifer, Moore, Jennifer, Banerjee, Rudrani, Yates, Phillip, Walker, Jill, Schnell, Gretja, Connolly, Mary Beth, Cathcart, Andrea L, Imber, Varsha, Anselm, Rabia, Winograd, Lindsay, Haeusser, Nancy, Segal, Scott, Skingsley, Andrew, Aldinger, Melissa, Peppercorn, Amanda, Moya, Jaynier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752959/
http://dx.doi.org/10.1093/ofid/ofac492.992