Challenges of using external data in clinical trials- an illustration in patients with COVID-19

BACKGROUND: To improve the efficiency of clinical trials, leveraging external data on control and/or treatment effects, which is almost always available, appears to be a promising approach. METHODS: We used data from the experimental arm of the Covidicus trial evaluating high-dose dexamethasone in s...

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Detalles Bibliográficos
Autores principales: Chevret, Sylvie, Timsit, Jean-François, Biard, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753019/
https://www.ncbi.nlm.nih.gov/pubmed/36522698
http://dx.doi.org/10.1186/s12874-022-01769-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753019/
https://www.ncbi.nlm.nih.gov/pubmed/36522698
http://dx.doi.org/10.1186/s12874-022-01769-5

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