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Challenges of using external data in clinical trials- an illustration in patients with COVID-19
BACKGROUND: To improve the efficiency of clinical trials, leveraging external data on control and/or treatment effects, which is almost always available, appears to be a promising approach. METHODS: We used data from the experimental arm of the Covidicus trial evaluating high-dose dexamethasone in s...
Autores principales: | Chevret, Sylvie, Timsit, Jean-François, Biard, Lucie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753019/ https://www.ncbi.nlm.nih.gov/pubmed/36522698 http://dx.doi.org/10.1186/s12874-022-01769-5 |
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