Germline BRCA2 variants in advanced pancreatic acinar cell carcinoma: A case report and review of literature

BACKGROUND: Pancreatic acinar cell carcinoma (PACC) is a rare tumor. Up to 45% of PACCs have alterations in the DNA damage repair pathway and 23% harbor rearrangements in the BRAF or RAF1 genes. We present a PACC case with a germline BRCA2 likely pathogenic variant (LPV) to highlight the impact of g...

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Detalles Bibliográficos
Autores principales: Lee, Cha Len, Holter, Spring, Borgida, Ayelet, Dodd, Anna, Ramotar, Stephanie, Grant, Robert, Wasson, Kristy, Elimova, Elena, Jang, Raymond W, Moore, Malcolm, Kim, Tae Kyoung, Khalili, Korosh, Moulton, Carol-Anne, Gallinger, Steven, O’Kane, Grainne M, Knox, Jennifer J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753052/
https://www.ncbi.nlm.nih.gov/pubmed/36533108
http://dx.doi.org/10.3748/wjg.v28.i45.6421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753052/
https://www.ncbi.nlm.nih.gov/pubmed/36533108
http://dx.doi.org/10.3748/wjg.v28.i45.6421

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