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Optimized Multi-Attribute Method Workflow Addressing Missed Cleavages and Chromatographic Tailing/Carry-Over of Hydrophobic Peptides

[Image: see text] Peptide mapping by liquid chromatography mass spectrometry (LC-MS) and the related multi-attribute method (MAM) are well-established analytical tools for verification of the primary structure and mapping/quantitation of co- and post-translational modifications (PTMs) or product qua...

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Detalles Bibliográficos
Autores principales: Kristensen, Dan B., Ørgaard, Martin, Sloth, Trine M., Christoffersen, Nanna S., Leth-Espensen, Katrine Z., Jensen, Pernille F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753059/
https://www.ncbi.nlm.nih.gov/pubmed/36346901
http://dx.doi.org/10.1021/acs.analchem.2c03820