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Three Component Cascade Reaction of Cyclohexanones, Aryl Amines, and Benzoylmethylene Malonates: Cooperative Enamine-Brønsted Acid Approach to Tetrahydroindoles

[Image: see text] A three-component cascade reaction comprising cyclic ketones, arylamines, and benzoylmethylene malonates has been developed to access 4,5,6,7-tetrahydro-1H-indoles. The reaction was achieved through cooperative enamine-Brønsted catalysis in high yields with wide substrate scopes. M...

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Detalles Bibliográficos
Autores principales: Cortes Vazquez, Jose, Alharbi, Waad S., Davis, Jacqkis, Moore, Alexia, Nesterov, Vladimir N., Cundari, Thomas R., Wang, Hong, Luo, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753174/
https://www.ncbi.nlm.nih.gov/pubmed/36530259
http://dx.doi.org/10.1021/acsomega.2c05909