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Strobealign: flexible seed size enables ultra-fast and accurate read alignment
Read alignment is often the computational bottleneck in analyses. Recently, several advances have been made on seeding methods for fast sequence comparison. We combine two such methods, syncmers and strobemers, in a novel seeding approach for constructing dynamic-sized fuzzy seeds and implement the...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753264/ https://www.ncbi.nlm.nih.gov/pubmed/36522758 http://dx.doi.org/10.1186/s13059-022-02831-7 |