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Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina

Microglia, the resident phagocytes of the retina, are believed to influence the development of retinopathy, but their exact contributions to vascular integrity and neuronal loss are unknown. Therefore, utilizing two models of microglia depletion, we aimed to deplete and repopulate microglia to clari...

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Detalles Bibliográficos
Autores principales: Church, Kaira A., Rodriguez, Derek, Vanegas, Difernando, Gutierrez, Irene L., Cardona, Sandra M., Madrigal, José L. M., Kaur, Tejbeer, Cardona, Astrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753268/
https://www.ncbi.nlm.nih.gov/pubmed/36517889
http://dx.doi.org/10.1186/s12974-022-02659-9