Sirtuin 5 aggravates microglia-induced neuroinflammation following ischaemic stroke by modulating the desuccinylation of Annexin-A1

BACKGROUND: Microglia-induced excessive neuroinflammation plays a crucial role in the pathophysiology of multiple neurological diseases, such as ischaemic stroke. Controlling inflammatory responses is considered a promising therapeutic approach. Sirtuin 5 (SIRT5) mediates lysine desuccinylation, whi...

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Detalles Bibliográficos
Autores principales: Xia, Qian, Gao, Shuai, Han, Tangrui, Mao, Meng, Zhan, Gaofeng, Wang, Yonghong, Li, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753274/
https://www.ncbi.nlm.nih.gov/pubmed/36517900
http://dx.doi.org/10.1186/s12974-022-02665-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753274/
https://www.ncbi.nlm.nih.gov/pubmed/36517900
http://dx.doi.org/10.1186/s12974-022-02665-x

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