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The traditional chinese medicine monomer Ailanthone improves the therapeutic efficacy of anti-PD-L1 in melanoma cells by targeting c-Jun

BACKGROUND: C-Jun, a critical component of AP-1, exerts essential functions in various tumors, including melanoma, and is believed to be a druggable target for cancer therapy. Unfortunately, no effective c-Jun inhibitors are currently approved for clinical use. The advent of immune checkpoint inhibi...

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Detalles Bibliográficos
Autores principales: Yu, Pian, Wei, Hui, Li, Kaixuan, Zhu, Shiguo, Li, Jie, Chen, Chao, Zhang, Detian, Li, Yayun, Zhu, Lei, Yi, Xiaoqing, Liu, Nian, Liu, Panpan, Zhao, Shuang, Chen, Xiang, Peng, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753288/
https://www.ncbi.nlm.nih.gov/pubmed/36522774
http://dx.doi.org/10.1186/s13046-022-02559-z