Cargando…

The traditional chinese medicine monomer Ailanthone improves the therapeutic efficacy of anti-PD-L1 in melanoma cells by targeting c-Jun

BACKGROUND: C-Jun, a critical component of AP-1, exerts essential functions in various tumors, including melanoma, and is believed to be a druggable target for cancer therapy. Unfortunately, no effective c-Jun inhibitors are currently approved for clinical use. The advent of immune checkpoint inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Pian, Wei, Hui, Li, Kaixuan, Zhu, Shiguo, Li, Jie, Chen, Chao, Zhang, Detian, Li, Yayun, Zhu, Lei, Yi, Xiaoqing, Liu, Nian, Liu, Panpan, Zhao, Shuang, Chen, Xiang, Peng, Cong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753288/ https://www.ncbi.nlm.nih.gov/pubmed/36522774 http://dx.doi.org/10.1186/s13046-022-02559-z

Ejemplares similares

Ailanthone inhibits non-small cell lung cancer cell growth through repressing DNA replication via downregulating RPA1
por: Ni, Zhongya, et al.
Publicado: (2017)

Ailanthone Induces Cell Cycle Arrest and Apoptosis in Melanoma B16 and A375 Cells
por: Liu, Wenjing, et al.
Publicado: (2019)

CD147 Facilitates the Pathogenesis of Psoriasis through Glycolysis and H3K9me3 Modification in Keratinocytes
por: Chen, Chao, et al.
Publicado: (2023)

Ailanthone: A novel potential drug for treating human cancer
por: Ding, Haixiang, et al.
Publicado: (2020)

Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer
por: He, Yundong, et al.
Publicado: (2016)

Ailanthone: a new potential drug for castration-resistant prostate cancer
por: Peng, Shihong, et al.
Publicado: (2017)

Ailanthone Inhibits Cell Proliferation in Tongue Squamous Cell Carcinoma via PI3K/AKT Pathway
por: Wang, Shuhan, et al.
Publicado: (2022)

Ailanthone induces autophagic and apoptotic cell death in human promyelocytic leukemia HL-60 cells
por: Wei, Cheng, et al.
Publicado: (2018)

Ailanthone Inhibits Proliferation, Migration and Invasion of Osteosarcoma Cells by Downregulating the Serine Biosynthetic Pathway
por: Zhang, Yawen, et al.
Publicado: (2022)

Ailanthone induces G(2)/M cell cycle arrest and apoptosis of SGC-7901 human gastric cancer cells
por: Chen, Yuxin, et al.
Publicado: (2017)

Physiological and Transcriptomic Analysis of Arabidopsis thaliana Responses to Ailanthone, a Potential Bio-Herbicide
por: Hopson, Chantz Allen, et al.
Publicado: (2022)

ASFV transcription reporter screening system identifies ailanthone as a broad antiviral compound
por: Zhang, Yuhang, et al.
Publicado: (2023)

Ailanthone Inhibits Huh7 Cancer Cell Growth via Cell Cycle Arrest and Apoptosis In Vitro and In Vivo
por: Zhuo, Zhenjian, et al.
Publicado: (2015)

Ailanthone Promotes Human Vestibular Schwannoma Cell Apoptosis and Autophagy by Downregulation of miR-21
por: Yang, Peizhen, et al.
Publicado: (2018)

Ailanthone suppresses the activity of human colorectal cancer cells through the STAT3 signaling pathway
por: Ding, Haixiang, et al.
Publicado: (2022)

Ailanthone inhibition data on seed germination and seedling growth of Lepidium sativum L. and Raphanus sativus L.
por: Demasi, Sonia, et al.
Publicado: (2019)

Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression
por: Wang, Chun-ming, et al.
Publicado: (2021)

TRAF6 regulates autophagy and apoptosis of melanoma cells through c‐Jun/ATG16L2 signaling pathway
por: Guo, Yeye, et al.
Publicado: (2023)

The role played by ailanthone in inhibiting bone metastasis of breast cancer by regulating tumor-bone microenvironment through the RANKL-dependent pathway
por: Wang, Yajun, et al.
Publicado: (2023)

Anti-BVDV Activity of Traditional Chinese Medicine Monomers Targeting NS5B (RNA-Dependent RNA Polymerase) In Vitro and In Vivo
por: Chen, Nannan, et al.
Publicado: (2023)

Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis
por: Liu, Nian, et al.
Publicado: (2023)

Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1
por: Liu, Nian, et al.
Publicado: (2023)

Harnessing the power of traditional Chinese medicine monomers and compound prescriptions to boost cancer immunotherapy
por: Miao, Keyan, et al.
Publicado: (2023)

Retraction: Liu, W., et al. Ailanthone Induces Cell Cycle Arrest and Apoptosis in Melanoma B16 and A375 Cells. Biomolecules 2019, 9, 275
Publicado: (2020)

miR‐493 by regulating of c‐Jun targets Wnt5a/PD‐L1‐inducing esophageal cancer cell development
por: Bian, Wei, et al.
Publicado: (2021)

The Anthelmintic Quassinoids Ailanthone and Bruceine a Induce Infertility in the Model Organism Caenorhabditis elegans by an Apoptosis-like Mechanism Induced in Gonadal and Spermathecal Tissues
por: Knetzger, Nicola, et al.
Publicado: (2021)

Recent Advances in Lignocellulose-Based Monomers and Their Polymerization
por: Pei, Fuyun, et al.
Publicado: (2023)

EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells
por: Shen, Xin, et al.
Publicado: (2023)

Quantitative proteomics approach to investigate the antibacterial response of Helicobacter pylori to daphnetin, a traditional Chinese medicine monomer
por: Lu, Yun, et al.
Publicado: (2021)

A novel ribosomal protein S6 kinase 2 inhibitor attenuates the malignant phenotype of cutaneous malignant melanoma cells by inducing cell cycle arrest and apoptosis
por: Li, Yayun, et al.
Publicado: (2022)

Anti-atherosclerosis mechanisms associated with regulation of non-coding RNAs by active monomers of traditional Chinese medicine
por: Liu, Guoqing, et al.
Publicado: (2023)

Enhanced histone H3 acetylation of the PD-L1 promoter via the COP1/c-Jun/HDAC3 axis is required for PD-L1 expression in drug-resistant cancer cells
por: Wang, Haifang, et al.
Publicado: (2020)

Pyroptosis: mechanisms and diseases
por: Yu, Pian, et al.
Publicado: (2021)

Evaluation of the teratogenic effects of three traditional Chinese medicines, Si Jun Zi Tang, Liu Jun Zi Tang and Shenling Baizhu San, during zebrafish pronephros development
por: Ding, Yu-Ju, et al.
Publicado: (2015)

Traditional Chinese Medicine Monomers: Novel Strategy for Endogenous Neural Stem Cells Activation After Stroke
por: Wang, Ju, et al.
Publicado: (2021)

c-JUN is a barrier in hESC to cardiomyocyte transition
por: Zhong, Hui, et al.
Publicado: (2023)

Traditional Chinese medicine monomers: Targeting pulmonary artery smooth muscle cells proliferation to treat pulmonary hypertension
por: Yang, Xiuli, et al.
Publicado: (2023)

Effect of traditional Chinese medicine monomers interfering with quorum-sensing on virulence factors of extensively drug-resistant Acinetobacter baumannii
por: Zeng, Li, et al.
Publicado: (2023)

Magnetic Molecularly Imprinted Polymers Based on Dehydroabietylamine as Chiral Monomers for the Enantioseparation of RS-Mandelic Acid
por: Wang, Yidan, et al.
Publicado: (2021)

Evaluation on the Pharmacological Effect of Traditional Chinese Medicine SiJunZiTang on Stress-Induced Peptic Ulcers
por: Chen, Chiu-Mei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_42935a5vld80eohc4a3o983rf9