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Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac(4)C acetylation of KIF23 mRNA

BACKGROUND: N(4)-acetylcytidine (ac(4)C) as a significant RNA modification has been reported to maintain the stability of mRNA and to regulate the translation process. However, the roles of both ac(4)C and its ‘writer’ protein N-acetyltransferase 10 (NAT10) played in the disease especially colorecta...

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Detalles Bibliográficos
Autores principales: Jin, Chi, Wang, Tuo, Zhang, Dongsheng, Yang, Peng, Zhang, Chuan, Peng, Wen, Jin, Kangpeng, Wang, Lu, Zhou, Jiahui, Peng, Chaofan, Tan, Yuqian, Ji, Jiangzhou, Chen, Zhihao, Sun, Qingyang, Yang, Sheng, Tang, Junwei, Feng, Yifei, Sun, Yueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753290/
https://www.ncbi.nlm.nih.gov/pubmed/36522719
http://dx.doi.org/10.1186/s13046-022-02551-7