Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype

BACKGROUND: Radiation-induced lung injury (RILI) often occurs during clinical chest radiotherapy and acute irradiation from accidental nuclear leakage. This study explored the role of monophosphoryl lipid A (MPLA) in RILI. MATERIALS AND METHODS: The entire thoracic cavity of C57BL/6N mice was irradi...

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Detalles Bibliográficos
Autores principales: Guo, Xingdong, Du, Lehui, Ma, Na, Zhang, Pei, Wang, Yuan, Han, Yanan, Huang, Xiang, Zhang, Qian, Tan, Xin, Lei, Xiao, Qu, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753357/
https://www.ncbi.nlm.nih.gov/pubmed/36517836
http://dx.doi.org/10.1186/s12967-022-03804-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753357/
https://www.ncbi.nlm.nih.gov/pubmed/36517836
http://dx.doi.org/10.1186/s12967-022-03804-x

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