Cargando…
Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis
BACKGROUND: In endothelial cells, phospholipase C (PLC) β1-activated Ca(2+) is a crucial second messenger for the signaling pathways governing angiogenesis. PLCβ1 is inactivated by complexing with an intracellular protein called translin-associated factor X (TRAX). This study demonstrates specific i...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753400/ https://www.ncbi.nlm.nih.gov/pubmed/36517806 http://dx.doi.org/10.1186/s12929-022-00889-w |