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Conformational alteration in glycan induces phospholipase Cβ1 activation and angiogenesis

BACKGROUND: In endothelial cells, phospholipase C (PLC) β1-activated Ca(2+) is a crucial second messenger for the signaling pathways governing angiogenesis. PLCβ1 is inactivated by complexing with an intracellular protein called translin-associated factor X (TRAX). This study demonstrates specific i...

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Detalles Bibliográficos
Autores principales:	Wang, Sheng-Hung, Cheng, Jing-Yan, Tsai, Hsiu-Hui, Lo, Tzu-Chi, Hung, Jung-Tung, Lin, Chun-Cheng, Lee, Chien-Wei, Ho, Yi-Hsuan, Kuo, Huan-Hsien, Yu, Alice L., Yu, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753400/ https://www.ncbi.nlm.nih.gov/pubmed/36517806 http://dx.doi.org/10.1186/s12929-022-00889-w

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