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Subcellular location of source proteins improves prediction of neoantigens for immunotherapy
Antigen presentation via the major histocompatibility complex (MHC) is essential for anti‐tumor immunity. However, the rules that determine which tumor‐derived peptides will be immunogenic are still incompletely understood. Here, we investigated whether constraints on peptide accessibility to the MH...
Autores principales: | Castro, Andrea, Kaabinejadian, Saghar, Yari, Hooman, Hildebrand, William, Zanetti, Maurizio, Carter, Hannah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753441/ https://www.ncbi.nlm.nih.gov/pubmed/36314681 http://dx.doi.org/10.15252/embj.2022111071 |
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