Intramembrane client recognition potentiates the chaperone functions of calnexin

One‐third of the human proteome is comprised of membrane proteins, which are particularly vulnerable to misfolding and often require folding assistance by molecular chaperones. Calnexin (CNX), which engages client proteins via its sugar‐binding lectin domain, is one of the most abundant ER chaperone...

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Detalles Bibliográficos
Autores principales: Bloemeke, Nicolas, Meighen‐Berger, Kevin, Hitzenberger, Manuel, Bach, Nina C, Parr, Marina, Coelho, Joao PL, Frishman, Dmitrij, Zacharias, Martin, Sieber, Stephan A, Feige, Matthias J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753464/
https://www.ncbi.nlm.nih.gov/pubmed/36314723
http://dx.doi.org/10.15252/embj.2022110959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753464/
https://www.ncbi.nlm.nih.gov/pubmed/36314723
http://dx.doi.org/10.15252/embj.2022110959

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