Novel 3-Methyleneisoindolinones Diversified via Intramolecular Heck Cyclization Induce Oxidative Stress, Decrease Mitochondrial Membrane Potential, Disrupt Cell Cycle, and Induce Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

[Image: see text] Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer in the world and the most prevalent cancer of developing countries. Increased disease burden and a smaller number of approved targeted therapies are a growing concern worldwide. Isoindolinone motifs ha...

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Detalles Bibliográficos
Autores principales: Sharma, Arti, Anand, Prince, Padwad, Yogendra S., Maurya, Sushil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753514/
https://www.ncbi.nlm.nih.gov/pubmed/36530328
http://dx.doi.org/10.1021/acsomega.2c05378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753514/
https://www.ncbi.nlm.nih.gov/pubmed/36530328
http://dx.doi.org/10.1021/acsomega.2c05378

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