Thieno[2,3-b]thiophene Derivatives as Potential EGFR(WT) and EGFRT(790M) Inhibitors with Antioxidant Activities: Microwave-Assisted Synthesis and Quantitative In Vitro and In Silico Studies

[Image: see text] Microwave-assisted synthesis and spectral analysis of certain novel derivatives of 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarbonitrile 1–7 were carried out. Compounds 1–7 were examined for cytotoxicity against MCF-7 and A549 cell lines using the quantitative MTT method, and gefiti...

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Detalles Bibliográficos
Autores principales: Ahmed, Sanaa A., Kamel, Moumen S., Aboelez, Moustafa O., Ma, Xiang, Al-Karmalawy, Ahmed A., Mousa, Sayed A. S., Shokr, Elders Kh., Abdel-Ghany, H., Belal, Amany, El Hamd, Mohamed A., Al Shehri, Zafer S., El Aleem Ali Ali El-Remaily, Mahmoud Abd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753534/
https://www.ncbi.nlm.nih.gov/pubmed/36530244
http://dx.doi.org/10.1021/acsomega.2c06219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753534/
https://www.ncbi.nlm.nih.gov/pubmed/36530244
http://dx.doi.org/10.1021/acsomega.2c06219

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