Multicomponent Synthesis of Diaminopurine and Guanine PNA’s Analogues Active against Influenza A Virus from Prebiotic Compounds

[Image: see text] Peptide nucleic acids (PNAs) play a key role in prebiotic chemistry as a chimera between RNA and proteins. We developed an alternative synthesis of bioactive PNA’s diaminopurine and guanine analogues from prebiotic compounds, such as aminomalononitrile (AMN), urea, and guanidine, u...

Descripción completa

Detalles Bibliográficos
Autores principales: Bizzarri, Bruno Mattia, Fanelli, Angelica, Ciprini, Stefania, Giorgi, Alessandra, De Angelis, Marta, Fioravanti, Raoul, Nencioni, Lucia, Saladino, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753540/
https://www.ncbi.nlm.nih.gov/pubmed/36530301
http://dx.doi.org/10.1021/acsomega.2c05754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753540/
https://www.ncbi.nlm.nih.gov/pubmed/36530301
http://dx.doi.org/10.1021/acsomega.2c05754

Ejemplares similares