Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance

BACKGROUND: Obesity and Type 2 Diabetes Mellitus (T2DM) are associated with an increased risk of severe outcomes from infectious diseases, including COVID-19. These conditions are also associated with distinct responses to immunization, including an impaired response to widely used SARS-CoV-2 mRNA v...

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Detalles Bibliográficos
Autores principales: O’Meara, Timothy R., Nanishi, Etsuro, McGrath, Marisa E., Barman, Soumik, Dong, Danica, Dillen, Carly, Menon, Manisha, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Ernst, Robert K., Levy, Ofer, Frieman, Matthew B., Dowling, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753785/
https://www.ncbi.nlm.nih.gov/pubmed/36523401
http://dx.doi.org/10.1101/2022.12.07.519460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753785/
https://www.ncbi.nlm.nih.gov/pubmed/36523401
http://dx.doi.org/10.1101/2022.12.07.519460

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