Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here, we perform longitudinal blood sampling of ESKD haemodialysis patients with COVID-19, collecting samples pre-infection, serially during infection, and after clinical recovery. Using plasma proteomics, and RNA-seq...

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Detalles Bibliográficos
Autores principales: Gisby, Jack S., Buang, Norzawani B., Papadaki, Artemis, Clarke, Candice L., Malik, Talat H., Medjeral-Thomas, Nicholas, Pinheiro, Damiola, Mortimer, Paige M., Lewis, Shanice, Sandhu, Eleanor, McAdoo, Stephen P., Prendecki, Maria F., Willicombe, Michelle, Pickering, Matthew C., Botto, Marina, Thomas, David C., Peters, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753891/
https://www.ncbi.nlm.nih.gov/pubmed/36522333
http://dx.doi.org/10.1038/s41467-022-35454-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753891/
https://www.ncbi.nlm.nih.gov/pubmed/36522333
http://dx.doi.org/10.1038/s41467-022-35454-4

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