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Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence
Patients with end-stage kidney disease (ESKD) are at high risk of severe COVID-19. Here, we perform longitudinal blood sampling of ESKD haemodialysis patients with COVID-19, collecting samples pre-infection, serially during infection, and after clinical recovery. Using plasma proteomics, and RNA-seq...
Autores principales: | Gisby, Jack S., Buang, Norzawani B., Papadaki, Artemis, Clarke, Candice L., Malik, Talat H., Medjeral-Thomas, Nicholas, Pinheiro, Damiola, Mortimer, Paige M., Lewis, Shanice, Sandhu, Eleanor, McAdoo, Stephen P., Prendecki, Maria F., Willicombe, Michelle, Pickering, Matthew C., Botto, Marina, Thomas, David C., Peters, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753891/ https://www.ncbi.nlm.nih.gov/pubmed/36522333 http://dx.doi.org/10.1038/s41467-022-35454-4 |
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