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Soluble TREM2 levels associate with conversion from mild cognitive impairment to Alzheimer’s disease

BACKGROUND: Soluble triggering receptor expressed on myeloid cells 2 (sTREM2) plays an important role in the clearance of pathological amyloid-β (Aβ) in Alzheimer’s disease (AD). This study aimed to explore sTREM2 as a central and peripheral predictor of the conversion from mild cognitive impairment...

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Detalles Bibliográficos
Autores principales: Zhao, Aonan, Jiao, Yang, Ye, Guanyu, Kang, Wenyan, Tan, Lan, Li, Yuanyuan, Deng, Yulei, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753995/
https://www.ncbi.nlm.nih.gov/pubmed/36519540
http://dx.doi.org/10.1172/JCI158708