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Thalamocortical circuits drive remifentanil-induced postoperative hyperalgesia
Remifentanil-induced hyperalgesia (RIH) is a severe but common postoperative clinical problem with elusive underlying neural mechanisms. Here, we discovered that glutamatergic neurons in the thalamic ventral posterolateral nucleus (VPL(Glu)) exhibited significantly elevated burst firing accompanied...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754001/ https://www.ncbi.nlm.nih.gov/pubmed/36519547 http://dx.doi.org/10.1172/JCI158742 |