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Thalamocortical circuits drive remifentanil-induced postoperative hyperalgesia

Remifentanil-induced hyperalgesia (RIH) is a severe but common postoperative clinical problem with elusive underlying neural mechanisms. Here, we discovered that glutamatergic neurons in the thalamic ventral posterolateral nucleus (VPL(Glu)) exhibited significantly elevated burst firing accompanied...

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Detalles Bibliográficos
Autores principales: Jin, Yan, Mao, Yu, Chen, Danyang, Tai, Yingju, Hu, Rui, Yang, Chen-Ling, Zhou, Jing, Chen, Lijian, Liu, Xuesheng, Gu, Erwei, Jia, Chunhui, Zhang, Zhi, Tao, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754001/
https://www.ncbi.nlm.nih.gov/pubmed/36519547
http://dx.doi.org/10.1172/JCI158742