Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice

The lymph node (LN) is the primary site of alloimmunity activation and regulation during transplantation. Here, we investigated how fibroblastic reticular cells (FRCs) facilitate the tolerance induced by anti-CD40L in a murine model of heart transplantation. We found that both the absence of LNs and...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Jung, Sungwook, Li, Xiaofei, Li, Lushen, Kasinath, Vivek, Zhang, Hengcheng, Movahedi, Said N., Mardini, Ahmad, Sabiu, Gianmarco, Hwang, Yoonha, Saxena, Vikas, Song, Yang, Ma, Bing, Acton, Sophie E., Kim, Pilhan, Madsen, Joren C., Sage, Peter T., Tullius, Stefan G., Tsokos, George C., Bromberg, Jonathan S., Abdi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754003/
https://www.ncbi.nlm.nih.gov/pubmed/36519543
http://dx.doi.org/10.1172/JCI159672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754003/
https://www.ncbi.nlm.nih.gov/pubmed/36519543
http://dx.doi.org/10.1172/JCI159672

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