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A novel model of gestational diabetes: Acute high fat high sugar diet results in insulin resistance and beta cell dysfunction during pregnancy in mice

Gestational diabetes mellitus (GDM) affects 7–18% of all pregnancies. Despite its high prevalence, there is no widely accepted animal model. To address this, we recently developed a mouse model of GDM. The goal of this work was to further characterize this animal model by assessing insulin resistanc...

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Detalles Bibliográficos
Autores principales: Mishra, Akansha, Ruano, Simone Hernandez, Saha, Pradip K., Pennington, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754171/
https://www.ncbi.nlm.nih.gov/pubmed/36520818
http://dx.doi.org/10.1371/journal.pone.0279041