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Human CYP2B6 produces oxylipins from polyunsaturated fatty acids and reduces diet-induced obesity

Multiple factors in addition to over consumption lead to obesity and non-alcoholic fatty liver disease (NAFLD) in the United States and worldwide. CYP2B6 is the only human detoxification CYP whose loss is associated with obesity, and Cyp2b-null mice show greater diet-induced obesity with increased s...

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Detalles Bibliográficos
Autores principales: Heintz, Melissa M., Eccles, Jazmine A., Olack, Emily M., Maner-Smith, Kristal M., Ortlund, Eric A., Baldwin, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754190/
https://www.ncbi.nlm.nih.gov/pubmed/36520866
http://dx.doi.org/10.1371/journal.pone.0277053