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Colchicine Drug Interaction Errors and Misunderstandings: Recommendations for Improved Evidence-Based Management

Colchicine is useful for the prevention and treatment of gout and a variety of other disorders. It is a substrate for CYP3A4 and P-glycoprotein (P-gp), and concomitant administration with CYP3A4/P-gp inhibitors can cause life-threatening drug–drug interactions (DDIs) such as pancytopenia, multiorgan...

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Detalles Bibliográficos
Autores principales: Hansten, Philip D., Tan, Malinda S., Horn, John R., Gomez-Lumbreras, Ainhoa, Villa-Zapata, Lorenzo, Boyce, Richard D., Subbian, Vignesh, Romero, Andrew, Gephart, Sheila, Malone, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754312/
https://www.ncbi.nlm.nih.gov/pubmed/36522578
http://dx.doi.org/10.1007/s40264-022-01265-1