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Colchicine Drug Interaction Errors and Misunderstandings: Recommendations for Improved Evidence-Based Management
Colchicine is useful for the prevention and treatment of gout and a variety of other disorders. It is a substrate for CYP3A4 and P-glycoprotein (P-gp), and concomitant administration with CYP3A4/P-gp inhibitors can cause life-threatening drug–drug interactions (DDIs) such as pancytopenia, multiorgan...
Autores principales: | Hansten, Philip D., Tan, Malinda S., Horn, John R., Gomez-Lumbreras, Ainhoa, Villa-Zapata, Lorenzo, Boyce, Richard D., Subbian, Vignesh, Romero, Andrew, Gephart, Sheila, Malone, Daniel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754312/ https://www.ncbi.nlm.nih.gov/pubmed/36522578 http://dx.doi.org/10.1007/s40264-022-01265-1 |
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