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Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa

Plasmodium ovale curtisi and P. ovale wallikeri are both endemic in sub-Saharan Africa, the Middle East and Southeast Asia. Molecular surveillance data for drug resistance in P. ovale spp. is limited at present. We analysed polymorphisms in the podhfr, pocrt and pocytb genes of P. ovale spp. in 147...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Ma, Xiaoqin, Tang, Jianxia, Xu, Sui, Gu, Yaping, Tang, Feng, Cao, Yuanyuan, Wang, Weiming, Zhou, Huayun, Zhang, Jiayao, Yu, Xinyu, Zhu, Guoding, Zhu, Meng, Zhang, Qingfeng, Culleton, Richard, Liu, Yaobao, Cao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754596/
https://www.ncbi.nlm.nih.gov/pubmed/36469541
http://dx.doi.org/10.1371/journal.pntd.0010977