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ToMExO: A probabilistic tree-structured model for cancer progression

Identifying the interrelations among cancer driver genes and the patterns in which the driver genes get mutated is critical for understanding cancer. In this paper, we study cross-sectional data from cohorts of tumors to identify the cancer-type (or subtype) specific process in which the cancer driv...

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Detalles Bibliográficos
Autores principales: Mohaghegh Neyshabouri, Mohammadreza, Lagergren, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754607/
https://www.ncbi.nlm.nih.gov/pubmed/36469540
http://dx.doi.org/10.1371/journal.pcbi.1010732