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Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

First recognized more than 30 years ago, glycine protects cells against rupture from diverse types of injury. This robust and widely observed effect has been speculated to target a late downstream process common to multiple modes of tissue injury. The molecular target of glycine that mediates cytopr...

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Detalles Bibliográficos
Autores principales: Borges, Jazlyn P, Sætra, Ragnhild SR, Volchuk, Allen, Bugge, Marit, Devant, Pascal, Sporsheim, Bjørnar, Kilburn, Bridget R, Evavold, Charles L, Kagan, Jonathan C, Goldenberg, Neil M, Flo, Trude Helen, Steinberg, Benjamin Ethan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
https://www.ncbi.nlm.nih.gov/pubmed/36468682
http://dx.doi.org/10.7554/eLife.78609